Vitamin B9, also known as folate or folic acid, is one of eight B vitamins that help the body turn food (carbohydrates) into fuel (glucose), which is used for energy. These B vitamins, often called B vitamins, help your body use fats and proteins. B vitamins are needed for a healthy liver and healthy skin, hair, and eyes. They also help the nervous system to function properly. Folic acid is the synthetic form of B9 found in dietary supplements and fortified foods, while folate is naturally present in foods.
Folic acid is essential for proper functioning of the brain and plays an important role in mental and emotional health. It helps in the production of DNA and RNA, the body's genetic material, and is especially important when cells and tissues are developing rapidly, such as during infancy, adolescence, and pregnancy. Folic acid also works closely with vitamin B12 to help form red blood cells and support the proper functioning of iron in the body. Vitamin B9 is a part of essential multivitamin that very effective to recover man and woman nutrition. Basically, multivitamin needs for women 40 up.
Vitamin B9 works with vitamins B6 and B12 and other nutrients to control blood levels of homocysteine, an amino acid. High levels of homocysteine are associated with heart disease, however, researchers do not know if homocysteine is a cause of heart disease or simply a marker, suggesting that.
It is quite common to have low levels of folic acid. Alcoholism, inflammatory bowel disease (IBD) and celiac disease can cause folic acid deficiency. In addition, some medications can reduce folate levels in the body. Folic acid deficiency can cause:
- Bad growth
- Inflammation of the tongue
- Gingivitis
- Anorexia
- Breathlessness
- Diarrhea
- Irritability
- Oversight
- Mental laziness
Pregnant women need more folic acid to reduce the risk of congenital neural tube defects such as cleft palate, spina bifida, and brain damage. Neural tube defects are congenital malformations caused by abnormal development of the neural tube; a structure that ultimately creates the brain and spinal cord. Since folic acid has been added to many cereal foods in the US UU. Like bread and cereals, neural tube defects have been significantly reduced.
Folate can Reduce the Risk of Cancer
A key factor in the formation of nucleic acids, folate plays an essential role in the synthesis, repair, and stability of DNA.
Folate coenzymes also regulate DNA methylation, which is essential for the control of gene expression and cell differentiation. The anomalies of this process have been linked to the development of mutations and cancers.
Low levels of folate in the blood are associated with certain types of cancer. Folate-rich nutrition has been shown to reduce the risk of multiple cancers (breast, pancreatic, colon, lung and esophageal cancers) in a series of observational studies.
Excessive consumption of folic acid (above the normal nutritional range) may, however, accelerate tumor growth in cancer patients, suggesting that the role of folate in preventing cancer development is dose-dependent.
The effects of folate on the suppression of cancer appear to also depend on the state of cell transformation at the time of initial folate exposure. In animal models of colorectal cancer, folic acid supplementation has been found to prevent the development of cancer in normal tissues, but to promote tumor growth in pre-existing areas of abnormal tissue growth.
Therefore, taking into account the dose and timing of folic acid supplementation is essential to prevent the growth of cancerous tissue.
Folate Promotes a Healthy Immune System
Often, increased susceptibility to infection in humans and animals with folate deficiency is observed.
Clinical deficiency of folate is often manifested as megaloblastic anemia, a condition that causes impaired immune responses (which primarily affect cell-mediated immunity). The elimination of folic acid deficiencies in the administration of dietary supplements restores immune function in affected patients.
A folate-rich diet was able to reverse age-related changes in T cell proliferation and cytokine production in rats, suggesting that folic acid supplements can be used in older adults to increase resistance to folate. infection.
Congenital Malformations
As mentioned earlier, pregnant women who do not consume enough folate are more likely to have children with congenital malformations. Pregnant women should receive 600 μg of folic acid daily. Women planning to become pregnant should ensure that they receive the recommended 400 μg daily, as many neural tube defects can occur shortly after conception and before a woman knows she is pregnant. Prenatal vitamins contain the necessary amount of folic acid for pregnant women.
Studies show that women taking folic acid supplements before conception and during the first trimester can reduce the risk of neural tube defects by 72 to 100%. Other studies suggest that folic acid supplementation in the context of folic acid grain accumulation does not appear to provide additional benefits for the prevention of spina bifida.
Folic acid can also help prevent spontaneous abortion, although the evidence is unclear. Child development studies indicate that prenatal folic acid supplementation at the time of conception is associated with a lower risk of autism. Other studies show that ingestion of folic acid preparations in early pregnancy is associated with a reduced risk of pronounced speech delay in 3-year-olds. And some research suggests that low levels of folate during pregnancy are associated with an increased risk of emotional problems in offspring.
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